2019/05/09
Rapid response to change driven by cross-species gene exchanges
"Gulf killifish have made a stunning comeback in Houston with the help of genetic mutations imported from interspecies mating with Atlantic killifish Scientists have suspected that mixing genes through hybridization 'can benefit populations experiencing rapid environmental change,' Clint Muhlfeld, an aquatic ecologist with the United States Geological Survey (USGS) who was not involved in the study, tells The Scientist in an email. 'But to my knowledge this is the first comprehensive study to directly and scientifically support this prediction." The paper itself is another nice example of bioinformatics methods helping understand bioloigy and new phenomena caused by human impact: "Given the limited migration of killifish, recent adaptive introgression was likely mediated by human-assisted transport. We suggest that interspecies connectivity may be an important source of adaptive variation during extreme environmental change." Full news article @ The Scientist and Original Article in Science.

Labels: #Adaptation, #change, #evolution
2018/05/08
Genetic adaptation in Humans helps deep divers
"The indigenous Bajau people (“Sea Nomads”) of Southeast Asia live a subsistence lifestyle based on breath-hold diving and are renowned for their extraordinary breath-holding abilities. However, it is unknown whether this has a genetic basis. Using a comparative genomic study, we show that natural selection on genetic variants in the PDE10A gene have increased spleen size in the Bajau, providing them with a larger reservoir of oxygenated red blood cells. We also find evidence of strong selection specific to the Bajau on BDKRB2, a gene affecting the human diving reflex. Thus, the Bajau, and possibly other diving populations, provide a new opportunity to study human adaptation to hypoxia tolerance." Full article @ Cell.
Labels: #Adaptation, #Diving, #Genetics, #Human